Sandrine de Ribaupierre

Maternal, Fetal & Newborn Health Dr. Sandrine de Ribaupierre
Associate Scientist


Associate Scientist, Division of Maternal, Fetal and Newborn Health, Children's Health Research Institute
Assistant Professor, Departments of Clinical Neurological Sciences - Neurosurgery, Surgery - Division of Paediatric Surgery, Paediatrics, Anatomy & Cell Biology, Medical Biophysics, Schulich School of Medicine & Dentistry, Western University 
Associate Member, The Brain and Mind Institute, Department of Psychology, Western University

How does my research help children?

Hydrocephalus is a common condition that leads to secondary deficits when not recognized and treated in time.  There are alot of unknowns for those patients, from the monitoring of increasing ventricular size after intraventricular hemorrhage in preterm infants and what is the best timing for intervention, to the understanding of how hydrocephalus might affect the brain.  Our research tries to answer some of those questions by providing new tools to monitor high risk patients, and incorporate them into clinical guidelines; as well as trying to understand some of the more fundamental changes brought by hydrocephalus in brain networks.


Current Research

Collaborating in the development of new bedside technolgoies to monitor brain function and hydrocephalus.  Those tools will enable a better monitoring of preterm infants at risk of post-hemorrhagic hydrocephalus, and guide clinicians in timing of their interventions.

We are also looking at brain network differences between children with hydrocephalus and healthy children.

Future Research Plans

Future research includes studying the mechanisms underlying the recofiguration of brain networks during development, in health controls, and in children with potential brain injury from intraventricular hemorrhage (IVH), using structural and functional MRI.  We are interested not only in stationary networks, but also how an individual's networks change over short time scales, and the relationship this has to behavioural variability.  Functional imaging will be used to study the brain regions activated during a task, and to establish broad connected networks while at rest.

Awards & Grants


Funding in support of "Healthcare simulation" - Awarded by Governemnt NCE - GRAND

Funding in support of "Surgical Simulator Design and Evaluation Using Game Engine Technology" - Awarded by MITACS

Funding in support of "New technologies in the management of post-hemorrhagic hydrocephalus in preterm infants" - Awarded by AMOSO AHSC AFP Innovation Fund

Recent Publications


Language mapping in temporal lobe epilepsy in children: Special considerations
de Ribaupierre S, Wang A, Hayman-Abello S
Epilepsy Research and Treatment. 2012

Functional Magnetic Resonance Imaging for Language Mapping in Temporal Lobe Epilepsy
Wang A, Peters T, de Ribaupierre S, Mirsattari S
Epilepsy Reserach and Treatment. 2012; 198183

Neurosurgical Management of Frontal Lobe Epilepsy in Children
Vachhrajani S, de Ribaupierre S, Otsubo H, Ochi A, Weiss S, Donner E, Widjaja E, Kerr E, Smith ML, Drake J, Rutka J
J Neurosurg Pediatr. 2012 Sep; 10(3):206-16

Unusual presentations of Chiari I in toddlers: Case reports and erview of the literature
Carew C, Tay KY, Prasad N, de Ribaupierre S
Childs Nerv Syst. 2012 June 3

Construction of a 3D anatomical model for teaching temporal lobectomy
de Ribaupierre S, Wilson T
Computers in Biology and Medicine. 2012

Evaluation of Neuroanatomical Training Using a 3D Visual Reality Model
Brewer D, Wilson T, Eagleson R, de Ribaupierre S
Studies in Health Technology and Informatics. 2012; 173:85-91

Presurgical language mapping in epileptic children: fMRI and depth electrode stimulation
de Ribaupierre S, Fohlen M, Bulteau C, Dorfmuller G, Delalande O, Jalin C, Dulac O, Chiron C, Hertz-Pannier L
Epilepsia. 2012 Jan; 53(1):67-78



Phone: (519) 685-8500, x58107
Fax: (519) 685-8171
E-mail: sderibau [at] uwo [dot] ca

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